Journal: The Journal of Headache and Pain

Article Title: Masticatory myalgia to headache-like secondary hypersensitivity induces gene plasticity at dura mater

doi: 10.1186/s10194-026-02361-8

Figure Lengend Snippet: Referred hypersensitivity following masseter muscle stimulation by collagenase type II. ( A ) Locations on the mouse head and neck areas used for von Frey testing to assess mechanical hypersensitivity. The blue arrow indicates the mandibular area, the green arrow marks the region over the masseter muscle (MM), and the red arrow denotes the periorbital area. ( B ) Schematic of experimental paradigms used for MM stimulation, including a single high-dose (10U) intramuscular injection of collagenase type II (Col; upper panel) and repetitive low-dose (0.2–0.5U) Col injections (lower panel). ( C ) Development of hypersensitivity over the MM area following vehicle (PBS) or a single 10U Col injection in male mice. ( D ) Development of periorbital mechanical hypersensitivity following a single vehicle (PBS) or 10U Col injection into the MM of male mice. ( E ) Development of hypersensitivity over the MM area following repetitive vehicle or 0.2–0.5U Col injections in male mice. ( F ) Periorbital mechanical hypersensitivity following repetitive vehicle or 0.2–0.5U Col injections into the MM of male mice. Panels C-F : statistical analysis are a two-way ANOVA with Bonferroni’s post-hoc test calculated relative to Veh (PBS) (* p < 0.05; ** p < 0.01; **** p < 0.0001; n = 6)

Article Snippet: Crude collagenase type II (Col; >125 units per mg; Cat: LS004214 ) preparations were acquired from Worthington (Lakewood, NJ).

Techniques: Injection

Journal: International Journal of Oral Science

Article Title: TGF-β2 downregulates osteogenesis under inflammatory conditions in dental follicle stem cells

doi: 10.1038/s41368-018-0028-8

Figure Lengend Snippet: Mass spectrometry analysis by comparison of normal and inflamed dental follicle in different bands of 1D-SDS-PAGE gel

Article Snippet: The collected DFSCs were incubated at 37 °C for 1 h in 3 mg · mL −1 type 1 collagenase (BioBasic INC., Toronto, ON, Canada) and 4 mg · mL −1 dispase II (Gibco-BRL, Waltham, MA, USA).

Techniques: Mass Spectrometry, Comparison, Binding Assay